Driving Discovery
through Metabolic Systems Biology
Re-imagining the metabolic basis of cancer and identifying previously unrecognized liabilities for therapeutic intervention.
About the Patti Lab
The Patti Lab is a research team at Washington University in St. Louis dedicated to pioneering innovative metabolomics, proteomics, and isotope-tracer technologies to study biochemical processes across scales. In addition to a scientifically diverse group of staff scientists and postdocs, the team consists of PhD students from multiple different programs including biochemistry, cancer biology, chemistry, computational and systems biology, developmental biology, molecular cell biology, and molecular genetics and genomics.
Areas of Research
Our research has three complementary themes. Team members who focus on different areas work together closely, with advances in one often inspiring developments in another.
Join Our Team
The Patti Lab has positions available at all levels, including:
- Postdoctoral Research Scholars
- Graduate Students
- Staff Scientists
- Mass Spectrometry Technologists/Research Associates
- Laboratory Managers
- Postdoctoral Fellowship in Cancer Metabolism
- Agilent-Merck Postdoctoral Fellowship
- Postdoctoral Fellowship in Multi-Omics Research
Center for Mass Spectrometry and Metabolic Tracing
The Center for Mass Spectrometry and Metabolic Tracing combines a breadth of instrumentation with advanced in-house informatics platforms to accommodate a wide range of applications such as metabolomics, lipidomics, exposomics, and proteomics. Equipment is regularly refreshed to continuously push the limits of measurement science. Technologies currently available include: GC/MS and LC/MS workflows; EI, ESI, DESI, and MALDI sources; time-of-flight and Orbitrap analyzers; trapped ion mobility spectrometry and traveling wave ion mobility spectroscopy; NMR spectrometers; and high-resolution respirometers.
NIH Center for Multi-Omics Production
The Patti Lab is proud to be part of the NIH Multi-Omics of Health and Disease Consortium. Partnering with the Wang Lab, we created the Washington University Omics Production Center to acquire whole genome sequencing, whole genome bisulfite sequencing, ATAC-seq, RNA-seq, proteomics, metabolomics, lipidomics, and exposomics data from the same set of disease samples provided by NIH Disease Study Sites.
